DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31546 and HSDL2

DIOPT Version :9

Sequence 1:NP_730973.1 Gene:CG31546 / 40691 FlyBaseID:FBgn0051546 Length:264 Species:Drosophila melanogaster
Sequence 2:NP_115679.2 Gene:HSDL2 / 84263 HGNCID:18572 Length:418 Species:Homo sapiens


Alignment Length:291 Identity:67/291 - (23%)
Similarity:106/291 - (36%) Gaps:74/291 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 SGKVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGHEPYGIAG------- 69
            :|..|.||||:.|||.|.|...:|.||.:.:..:..:....::........|...:.|       
Human     9 AGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIV 73

  Fly    70 DLLKPPEIECIARKTTERYEGKLDVLVNGA-GIMPTGTLQSTELACFTHVMEANVRSGFYLTKLL 133
            |:....:|.....|..::: |.:|:|||.| .|..|.|| .|.......:|..|.|..:..:|..
Human    74 DVRDEQQISAAVEKAIKKF-GGIDILVNNASAISLTNTL-DTPTKRLDLMMNVNTRGTYLASKAC 136

  Fly   134 LPQLLQCK-GSIVNVSSVCGLRA--FPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAV----- 190
            :|.|.:.| ..|:|:|....|..  |....||.::|..:..:...:|.:...: :.|||:     
Human   137 IPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEFKGE-IAVNALWPKTA 200

  Fly   191 ----------NPG-----------------------------VIRTNLQKAGGMDE-QSYA---- 211
                      .||                             ||..|:.|..|::. ..||    
Human   201 IHTAAMDMLGGPGIESQCRKVDIIADAAYSIFQKPKSFTGNFVIDENILKEEGIENFDVYAIKPG 265

  Fly   212 ------EFLEH-----SKKTHALGRIGEPKE 231
                  .||:.     |||..:.|.:.|.||
Human   266 HPLQPDFFLDEYPEAVSKKVESTGAVPEFKE 296

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31546NP_730973.1 fabG 9..257 CDD:235975 67/291 (23%)
NADB_Rossmann 11..261 CDD:304358 67/291 (23%)
HSDL2NP_115679.2 HSDL2_SDR_c 8..248 CDD:187663 53/241 (22%)
SCP2 319..412 CDD:376720
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0725
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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