Protein Alignment CG31546 and Hsd17b14

DIOPT Version :10

• Sequence 1: NP_730973.1
• Gene: CG31546 / 40691
• FlyBaseID: FBgn0051546
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_079606.3
• Gene: Hsd17b14 / 66065
• MGIID: 1913315
• Length: 273
• Species: Mus musculus
• Alignment Length: 255
• Identity: 96/255 - (37%)
• Similarity: 139/255 - (54%)
• Gaps: 15/255 - (5%)

  Fly    11 FSGKVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGHEPYG---IAGDLL 72
            :|||||::||.:.|||||....|...||.:...|::|.|     .|.::  .|..|   |.||:.
Mouse     7 YSGKVVVVTGGSRGIGAAIVRAFVDSGAQVVFCDKDEAG-----GRALE--QELSGTVFIPGDVT 64

  Fly    73 KPPEIECIARKTTERYEGKLDVLVNGAGIMPTGTL-QSTELACFTHVMEANVRSGFYLTKLLLPQ 136
            :..:::.:..:|..|: |.||.:||.||..|...| :.|....|..::|.|:...:.|.||.||.
Mouse    65 QERDLQTLVSETLSRF-GHLDCVVNNAGYHPPAQLPEETSAQGFRQLLEVNLLGTYTLIKLALPH 128

  Fly   137 LLQCKGSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAVNPGVIRTNL-Q 200
            |.:.:|:|:|:||:.|.......:.|..:|.||...|::||||....|||||.::||.|.|.| :
Mouse   129 LRKSRGNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRHGVRVNCISPGNIWTPLWE 193

  Fly   201 KAGGMDEQSYAEFLEHSKKTHALGRIGEPKEVAAAICFLASELASFVTGVTLPVDGGKQV 260
            :.........|..|| ......|||:|:|.|||||..||||| |:|.||:.|.|.||.::
Mouse   194 ELAASTSDPRATILE-GTLAQPLGRMGQPAEVAAAAVFLASE-ATFCTGLELLVTGGAEL 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31546	NP_730973.1	Rossmann-fold NAD(P)(+)-binding proteins	11..261	CDD:473865	96/255 (38%)
Hsd17b14	NP_079606.3	Rossmann-fold NAD(P)(+)-binding proteins	1..256	CDD:473865	96/255 (38%)