DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31546 and hsd17b8

DIOPT Version :9

Sequence 1:	NP_730973.1	Gene:	CG31546 / 40691	FlyBaseID:	FBgn0051546	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001016671.1	Gene:	hsd17b8 / 549425	XenbaseID:	XB-GENE-490296	Length:	255	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	69/248 - (27%)
Similarity:	115/248 - (46%)	Gaps:	11/248 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMK--MGHEPYGIAGDLLKPPEI 77
            :.|:||..||||.|..:..|..||.:.:||.:.......::....  .|.|....|.|:.|...:
Frog    11 LALVTGGGSGIGRAICQRLSVEGASVVVVDLDISSANATLQTLSHNLSGQEHAAFATDVSKANHV 75

  Fly    78 ECIARKTTERYEGKLDVLVNGAGIMPTGTLQSTELACFTHVMEANVRSGFYLTKLLLPQLL---Q 139
            ..:.:|...||.....:.::.|||.....|.......|..|:..|::..|.:|:.:...::   :
Frog    76 NSLMQKIQGRYSVPPRIAISSAGITKDEFLLRLSEESFDSVLNVNLKGPFLITQAVARAIVASGE 140

  Fly   140 CKGSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAVNPGVIRTNLQKAGG 204
            ..|||:|:.|:.|.........|..|||.|:..|::.|.:|...|:|.|.|.||.|.|      .
Frog   141 HGGSIINIGSIVGKVGNLGQSNYAASKAGVEGLTKTAAKELAKFGIRCNTVLPGFIST------P 199

  Fly   205 MDEQSYAEFLEHSKKTHALGRIGEPKEVAAAICFLASELASFVTGVTLPVDGG 257
            |.::...:.|:.......|||:|.|:::|....||||:.:.::||.::.|.||
Frog   200 MTDKVPQKVLDKFAGMVPLGRLGYPEDIADVCAFLASDDSKYITGASIEVTGG 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31546	NP_730973.1	fabG	9..257	CDD:235975	67/246 (27%)
CG31546	NP_730973.1	NADB_Rossmann	11..261	CDD:304358	69/248 (28%)
hsd17b8	NP_001016671.1	BKR_SDR_c	11..254	CDD:187594	69/248 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000