Protein Alignment CG31546 and hsd17b14

DIOPT Version :10

• Sequence 1: NP_730973.1
• Gene: CG31546 / 40691
• FlyBaseID: FBgn0051546
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_001003521.1
• Gene: hsd17b14 / 445127
• ZFINID: ZDB-GENE-040801-24
• Length: 271
• Species: Danio rerio
• Alignment Length: 267
• Identity: 72/267 - (26%)
• Similarity: 124/267 - (46%)
• Gaps: 32/267 - (11%)

  Fly    11 FSGKVVLITGAASGIGAAAAEMF----SKLGACL------------ALVDREEEGLICVMKRCMK 59
            :..|||::||...|||....:.|    ||:..|.            :::::|..| .|....|
Zfish     7 YQNKVVIVTGGTRGIGRGIVKTFVQNGSKVVFCAPQTEMSAGQSLESVLNKEGPG-SCKFVSC-- 68

  Fly    60 MGHEPYGIAGDLLKPPEIECIARKTTERYEGKLDVLVNGAGIMPT-GTLQSTELACFTHVMEANV 123
                      |:.:..:|:.:...|.|.: |::|.|||..|..|. .|...|....|..::..|:
Zfish    69 ----------DMREEEDIKQLINVTVESF-GQIDCLVNNVGWHPPHKTTDETSGEEFKDLLNLNL 122

  Fly   124 RSGFYLTKLLLPQLLQCKGSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVN 188
            .|.|..:|..||.|.:.:|:|:|:||:.......:...|..:|.|:...|:::|:|.....||||
Zfish   123 ISFFLASKYALPYLRKTQGNIINLSSLVASIGQKDAAPYVATKGAITAMTKAMAVDESRYQVRVN 187

  Fly   189 AVNPGVIRTNLQKAGGMDEQSYAEFLEHSKKTHALGRIGEPKEVAAAICFLASELASFVTGVTLP 253
            .::|..|.|.|.:....:.:..|..::..:....:||:|...|...|..|||:: |:|.||:.|.
Zfish   188 CISPSNIMTPLWEELAANTEDTAATIKGGEDAQLIGRMGTEAESGLAALFLAAD-ATFCTGIDLF 251

  Fly   254 VDGGKQV 260
            :.||.::
Zfish   252 LSGGAEL 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31546	NP_730973.1	Rossmann-fold NAD(P)(+)-binding proteins	11..261	CDD:473865	72/267 (27%)
hsd17b14	NP_001003521.1	RDH_SDR_c	1..263	CDD:187638	72/267 (27%)