Protein Alignment CG31546 and HSD11B1L

DIOPT Version :10

• Sequence 1: NP_730973.1
• Gene: CG31546 / 40691
• FlyBaseID: FBgn0051546
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_001254797.1
• Gene: HSD11B1L / 374875
• HGNCID: 30419
• Length: 333
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 79/243 - (32%)
• Similarity: 109/243 - (44%)
• Gaps: 19/243 - (7%)

  Fly    13 GKVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMG-HEPYGIAGDLLKPPE 76
            |..||:|||.:|:|...|..:::||:.|.|....|..|..|:..|.|:| .:.:.||.|:..|..
Human    76 GARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEA 140

  Fly    77 IECIARKTTERYEGKLDVLV-NGAGIMPTGTLQSTELACFTHVMEANVRSGFYLTKLLLPQLLQC 140
            .|.:.:...::. |.||.|| |..|..|.||...:..|. ..:|:.|..|...||...||.|...
Human   141 PESVVQFALDKL-GGLDYLVLNHIGGAPAGTRARSPQAT-RWLMQVNFVSYVQLTSRALPSLTDS 203

  Fly   141 KGSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAVNPGVIRTNLQKAGGM 205
            |||:|.|||:.|.........|:.:|.|:|.|..||..:|..|.|.| |:...|:       |..
Human   204 KGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV-AITMCVL-------GLR 260

  Fly   206 DEQSYAEFLEHSKKTHALGRIGEPKEVAAAICFLASELASFVTGVTLP 253
            |..|.||.:....:..|   ...||...|.|...|:..|    ||..|
Human   261 DRASAAEAVRGVTRVKA---APGPKAALAVIRGGATRAA----GVFYP 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31546	NP_730973.1	Rossmann-fold NAD(P)(+)-binding proteins	11..261	CDD:473865	79/243 (33%)
HSD11B1L	NP_001254797.1	Rossmann-fold NAD(P)(+)-binding proteins	74..302	CDD:473865	79/243 (33%)