DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31546 and dhs-6

DIOPT Version :9

Sequence 1:	NP_730973.1	Gene:	CG31546 / 40691	FlyBaseID:	FBgn0051546	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001021972.1	Gene:	dhs-6 / 3565470	WormBaseID:	WBGene00000970	Length:	418	Species:	Caenorhabditis elegans

Alignment Length:	242	Identity:	61/242 - (25%)
Similarity:	101/242 - (41%)	Gaps:	29/242 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGSKGKAGLDFSGKVVLITGAASGIGAAAAEMFSKLGACLALVDREEEG-------LICVMKRCM 58
            |.:.||    |.|:.||||||:.|||...|...:|.||.:.:..:....       :....:...
Worm     1 MFNTGK----FVGRTVLITGASRGIGKEIALKLAKDGANIVVAAKTATAHPKLPGTIYSAAEEIE 61

  Fly    59 KMGHEPYGIAGDLLKPPEIECIARKTTERYEGKLDVLVNGAGIMPTGTLQSTELACFTHVMEANV 123
            |.|.:......|:.....::....:..::: |.:|:|:|.|..:.....::||:..:..:...|.
Worm    62 KAGGKALPCIVDVRDEASVKASVEEAVKKF-GGIDILINNASAISLTDTENTEMKRYDLMHSINT 125

  Fly   124 RSGFYLTKLLLPQLLQCKG-SIVNVSS--VCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGV 185
            |..|.:||..||.|...|. .::|:|.  :...|.|.|.|||.|:|..:.........:..|.|:
Worm   126 RGTFLMTKTCLPYLKSGKNPHVLNISPPLLMETRWFANHVAYTMAKYGMSMCVLGQHEEFRPHGI 190

  Fly   186 RVNAVNP-----GVIRTNLQKAGG---------MDEQSYAEFLEHSK 218
            .|||:.|     ......|...||         |.:.:||...::||
Worm   191 AVNALWPLTAIWTAAMEMLSDKGGEAGSRKPSIMADAAYAVLSKNSK 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31546	NP_730973.1	fabG	9..257	CDD:235975	58/234 (25%)
CG31546	NP_730973.1	NADB_Rossmann	11..261	CDD:304358	58/232 (25%)
dhs-6	NP_001021972.1	PRK08278	9..275	CDD:181349	57/230 (25%)
dhs-6	NP_001021972.1	SCP2	319..411	CDD:376720
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156031
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.830