DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31546 and hsdl2

DIOPT Version :9

Sequence 1:	NP_730973.1	Gene:	CG31546 / 40691	FlyBaseID:	FBgn0051546	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_955893.1	Gene:	hsdl2 / 322347	ZFINID:	ZDB-GENE-030131-1066	Length:	415	Species:	Danio rerio

Alignment Length:	253	Identity:	63/253 - (24%)
Similarity:	105/253 - (41%)	Gaps:	66/253 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SGKVVLITGAASGIGAAAAEMFSKLGACLALVDREEE----------------------GLICVM 54
            :|..:.||||:.|||.|.|...::.||.:.:..:..:                      .|.|::
Zfish     9 AGCTIFITGASRGIGKAIALKAAQDGANVVIAAKTADPHPKLPGTIYTAAAEIEAAGGKALPCIV 73

  Fly    55 KRCMKMGHEPYGIAGDLLKPPEIECIARKTTERYEGKLDVLVNGA-GIMPTGTLQSTELACFTHV 118
                           |:....:|.....:..|:: |.:|:|||.| .|..||||| |.:.....:
Zfish    74 ---------------DVRDEKQINDAVEQAVEKF-GGIDILVNNASAINLTGTLQ-TPMKKADLM 121

  Fly   119 MEANVRSGFYLTKLLLPQLLQCKG-SIVNVSSVCGLRA--FPNLVAYNMSKAAVDQFTRSLALDL 180
            :..|:|..:..:||.:|.||:.|. .|:|:|....|..  |.|..||.::|..:......:|.:.
Zfish   122 LGINLRGTYLTSKLCIPHLLKSKNPHILNLSPPLNLNPIWFKNHTAYTIAKYGMSMCVLGMAEEF 186

  Fly   181 GPQG-VRVNAVNPGVIRTNLQKA-----GG------------MDEQSYAEFLEHSKKT 220
              :| :.|||:.|   :|.:|.|     ||            |.:.:||.|.:.:..|
Zfish   187 --RGSIAVNALWP---KTAIQTAAMDMLGGSEVGKQCRKVEIMADAAYAIFKQPTSFT 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31546	NP_730973.1	fabG	9..257	CDD:235975	63/253 (25%)
CG31546	NP_730973.1	NADB_Rossmann	11..261	CDD:304358	63/253 (25%)
hsdl2	NP_955893.1	HSDL2_SDR_c	8..248	CDD:187663	63/253 (25%)
		adh_short	12..210	CDD:278532	55/219 (25%)
		SCP2	311..408	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900