Protein Alignment CG31546 and Hsd17b8

DIOPT Version :10

• Sequence 1: NP_730973.1
• Gene: CG31546 / 40691
• FlyBaseID: FBgn0051546
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_038571.2
• Gene: Hsd17b8 / 14979
• MGIID: 95911
• Length: 259
• Species: Mus musculus
• Alignment Length: 256
• Identity: 76/256 - (29%)
• Similarity: 119/256 - (46%)
• Gaps: 23/256 - (8%)

  Fly    15 VVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGHE---PYG----IAGDLL 72
            :.|:|||.||||.|.:...:..||.:|..|.:.......::.....|.|   |.|    ...|:.
Mouse    11 LALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSEDGAPRGKHAAFQADVS 75

  Fly    73 KPPEIECIARKTTERYEGKLDVLVNGAGIMPTGTLQSTELACFTHVMEANVRSGFYLTKLLLPQL 137
            :.|....:..:....:.....|:|:.|||.....|.......:..|:..|::..|.:|:.....|
Mouse    76 QGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDRVIAVNLKGTFLVTQAAAQAL 140

  Fly   138 LQC--KGSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAVNPGVIRTNL- 199
            :..  :|||:|:||:.|.........|..|||.|...|::.|.:||..|:|.|:|.||.|.|.:
Mouse   141 VSSGGRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMT 205

  Fly   200 QKAGGMDEQSYAEFLEHSKKTHA---LGRIGEPKEVAAAICFLASELASFVTGVTLPVDGG 257
            ||   |.|:.       ..|..|   ||.:|:|::||..:.|||||.:.::||.::.|.||
Mouse   206 QK---MPEKV-------KDKVTAMIPLGHMGDPEDVADVVAFLASEDSGYITGASVEVSGG 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31546	NP_730973.1	Rossmann-fold NAD(P)(+)-binding proteins	11..261	CDD:473865	76/256 (30%)
Hsd17b8	NP_038571.2	Rossmann-fold NAD(P)(+)-binding proteins	11..258	CDD:473865	76/256 (30%)