Protein Alignment CG31546 and hsd17b14

DIOPT Version :10

• Sequence 1: NP_730973.1
• Gene: CG31546 / 40691
• FlyBaseID: FBgn0051546
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: XP_002935043.1
• Gene: hsd17b14 / 100498205
• XenbaseID: XB-GENE-986127
• Length: 276
• Species: Xenopus tropicalis
• Alignment Length: 282
• Identity: 82/282 - (29%)
• Similarity: 133/282 - (47%)
• Gaps: 49/282 - (17%)

  Fly     3 SKGKAGLDFSGKVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLI------------CVMK 55
            |..:..|.:..:|.:|||...|||.|..:.|.|.||.:....::.|...            |:..
 Frog     4 SGAELSLRYRDRVAVITGGTKGIGEAMVKEFVKSGARVVFCSKDTEAKALENEIKAAGPGDCIYV 68

  Fly    56 RCMKMGHEPYGIAGDLLKPPEIECIARKTTERYEGKLDVLVNGAG-IMPTGTLQSTELACFTHVM 119
            .|            |:.|..:|:.:...|...| |::|.|:|.|| ..|..|:..|....|..::
 Frog    69 CC------------DVTKEEDIKKLIEITVMNY-GQIDCLINNAGWHPPEQTIDGTSADDFRDLL 120

  Fly   120 EANVRSGFYLT-KLLLPQLLQCKGSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQ 183
            ..|: .|::|| |..||.|.:.:|:|:|:||:.|:....:.:.|..:|.||...|:::|:|....
 Frog   121 NLNL-IGYFLTAKYALPHLRKTQGNIINISSLVGIIGQKHAIPYVATKGAVTAMTKAMAVDESRH 184

  Fly   184 GVRVNAVNPGVIRTNLQKAGGMDEQSYAEFLEHSKKTHA----------LGRIGEPKEVAAAICF 238
            .||:|:::||.|.|.|          :.|...|||.:.|          |||:|..:|.|.|..:
 Frog   185 NVRINSISPGNIWTPL----------WEELSSHSKNSEAMIQGGIDAQLLGRMGTAEECAKAALY 239

  Fly   239 LASELASFVTGVTLPVDGGKQV 260
            ||:| .:|.||:.|.:.||.::
 Frog   240 LAAE-GTFCTGIDLLLTGGAEL 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31546	NP_730973.1	Rossmann-fold NAD(P)(+)-binding proteins	11..261	CDD:473865	80/274 (29%)
hsd17b14	XP_002935043.1	Rossmann-fold NAD(P)(+)-binding proteins	6..265	CDD:473865	81/280 (29%)