Protein Alignment CG12171 and ucpA

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_416921.4
• Gene: ucpA / 946898
• ECOCYCID: EG12133
• Length: 263
• Species: Escherichia coli
• Alignment Length: 259
• Identity: 90/259 - (34%)
• Similarity: 139/259 - (53%)
• Gaps: 16/259 - (6%)

  Fly     1 MPSFKDKVIIVTGASSGIGAGTSVLLAKLGG--LLTIVGRNLDKLNETAEQIVAAGGAPALQVAA 63
            |.....|..::|||..|||.|.:...|:.|.  :|..:...::||   |:::...|.. ...|.|
E. coli     1 MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEKL---ADELCGRGHR-CTAVVA 61

  Fly    64 DINSESDVQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTP 128
            |:...:.|...:.....|.||||:||||||:..|||..:.|.:..|..::.|::.::.:|..|.|
E. coli    62 DVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMSDDDRDFHIDINIKGVWNVTKAVLP 126

  Fly   129 ELIKTK-GNIVNVSSVNG-IRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITE 191
            |:|..| |.||.:|||.| :.:.||..||.::|||:...|:.:|:|.|..|:|||::.||.:.|.
E. coli   127 EMIARKDGRIVMMSSVTGDMVADPGETAYALTKAAIVGLTKSLAVEYAQSGIRVNAICPGYVRTP 191

  Fly   192 L-----QRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250
            :     ::....|.|:.:..:..|.....|..|.||.|:|   |||||||:|:.||....:|||
E. coli   192 MAESIARQSNPEDPESVLTEMAKAIPMRRLADPLEVGELA---AFLASDESSYLTGTQNVIDGG 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	89/256 (35%)
ucpA	NP_416921.4	PRK08226	1..263	CDD:181305	90/259 (35%)