Protein Alignment CG12171 and hcaB

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_417036.1
• Gene: hcaB / 945346
• ECOCYCID: G7335
• Length: 270
• Species: Escherichia coli
• Alignment Length: 216
• Identity: 59/216 - (27%)
• Similarity: 94/216 - (43%)
• Gaps: 32/216 - (14%)

  Fly     1 MPSFKDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAG---------GA 56
            |....::.|.:||..||:|             |.:|.|.:::..:.|...::|.         |.
E. coli     1 MSDLHNESIFITGGGSGLG-------------LALVERFIEEGAQVATLELSAAKVASLRQRFGE 52

  Fly    57 PALQVAADINSESDVQGIVSATLAKHGRIDVLVNNAGILE-LGSIENTSLEQ----FDRVMNTNV 116
            ..|.|..::...:|.|..|...|.:.|::|..:.||||.: ..|:.||..|.    |..:.|.||
E. coli    53 HILAVEGNVTCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPAETLETGFHELFNVNV 117

  Fly   117 RSLYQLTHLVTPELIKTKGNIVNVSSVNGIRSFP--GVLAYNVSKAAVDQFTRCVALELAPKGVR 179
            ...........|.||.::|::  :.:::....:|  |...|..||.|.....|.:|.||||| ||
E. coli   118 LGYLLGAKACAPALIASEGSM--IFTLSNAAWYPGGGGPLYTASKHAATGLIRQLAYELAPK-VR 179

  Fly   180 VNSVNPGVIITELQRRGGLDQ 200
            ||.|.|..:.::|:....|.|
E. coli   180 VNGVGPCGMASDLRGPQALGQ 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	58/213 (27%)
hcaB	NP_417036.1	BphB-like_SDR_c	3..259	CDD:187606	58/214 (27%)