Protein Alignment CG12171 and CBR3

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_001227.1
• Gene: CBR3 / 874
• HGNCID: 1549
• Length: 277
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 57/258 - (22%)
• Similarity: 103/258 - (39%)
• Gaps: 63/258 - (24%)

  Fly     7 KVIIVTGASSGIG-AGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESD 70
            :|.:||||:.||| |....|..:..|.:.:..|::.:.....:|:.|.|.:|... ..||:....
Human     6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFH-QLDIDDLQS 69

  Fly    71 VQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFD----RVMNTNVRSLYQLTHLVTPELI 131
            ::.:......::|.::||||||.:    :.::.....||    ..:.||..:...:.:.:.| ::
Human    70 IRALRDFLRKEYGGLNVLVNNAAV----AFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLP-IM 129

  Fly   132 KTKGNIVNVSSVNGIRSF-----------------PGVLA------------------------Y 155
            |..|.:||:||:..:|:|                 .|.|.                        |
Human   130 KPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPY 194

  Fly   156 NVSKAAVDQFTRCVALELAPK----GVRVNSVNPGVIITELQRRG-------GLDQEAYVKFL 207
            .|||..|...:|.:|..|..|    .:.||:..||.:.|::..:.       |.:...|:..|
Human   195 GVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALL 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	57/258 (22%)
CBR3	NP_001227.1	carb_red_PTCR-like_SDR_c	6..277	CDD:187585	57/258 (22%)