Protein Alignment CG12171 and ORA1

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_013953.1
• Gene: ORA1 / 855266
• SGDID: S000004839
• Length: 267
• Species: Saccharomyces cerevisiae
• Alignment Length: 258
• Identity: 80/258 - (31%)
• Similarity: 118/258 - (45%)
• Gaps: 28/258 - (10%)

  Fly     7 KVIIVTGASSGIGAGTSV--LLAKLGGL-LTIVGRNLDKLNETAEQIVAAGGAPALQVA-ADINS 67
            |.:::||||:|||..|::  |.|..|.: |.:..|.|:||.|..:.|........:.|| .||..
Yeast    14 KTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQLDITQ 78

  Fly    68 ESDVQGIVSATLAKHGRIDVLVNNAGILELGS--IENTSLEQFDRVMNTNVRSLYQLTHLVTPEL 130
            ...::..:.....:...||:|||||| ..|||  :...:.|....|.:|||.:|..:|..|.|..
Yeast    79 AEKIKPFIENLPQEFKDIDILVNNAG-KALGSDRVGQIATEDIQDVFDTNVTALINITQAVLPIF 142

  Fly   131 -IKTKGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITE--- 191
             .|..|:|||:.|:.|..::|....|..||.||..||..:..||....:||..:.||::.||
Yeast   143 QAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINTKIRVILIAPGLVETEFSL 207

  Fly   192 LQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLAS--------DEASFSTGISLP 246
            ::.||..:|         ||..:....|....:||..|.:..|        |...|.|..:.|
Yeast   208 VRYRGNEEQ---------AKNVYKDTTPLMADDVADLIVYATSRKQNTVIADTLIFPTNQASP 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	80/258 (31%)
ORA1	NP_013953.1	SDR_c5	14..266	CDD:187604	80/258 (31%)