Protein Alignment CG12171 and IRC24

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_012302.3
• Gene: IRC24 / 854854
• SGDID: S000001475
• Length: 263
• Species: Saccharomyces cerevisiae
• Alignment Length: 256
• Identity: 79/256 - (30%)
• Similarity: 122/256 - (47%)
• Gaps: 51/256 - (19%)

  Fly     7 KVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIV-----AAGGAPALQ------ 60
            |||::||||.|||    :.|.|     |::       .|..|.||     ...|..:||
Yeast     3 KVILITGASRGIG----LQLVK-----TVI-------EEDDECIVYGVARTEAGLQSLQREYGAD 51

  Fly    61 ----VAADINSESDVQGIVSATLAKHGRIDVLVNNAGILE-LGSIENTS----LEQFDRVMNTNV 116
                ...||...|.::.:|.....|||::|.:|.|||:|| :.||..::    ::|::|:.:.|.
Yeast    52 KFVYRVLDITDRSRMEALVEEIRQKHGKLDGIVANAGMLEPVKSISQSNSEHDIKQWERLFDVNF 116

  Fly   117 RSLYQLTHLVTPELIKTK---GNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGV 178
            .|:..|..|..| |:|:.   ||||.|||...::.:.|..||..||||::.|...:|.|.....|
Yeast   117 FSIVSLVALCLP-LLKSSPFVGNIVFVSSGASVKPYNGWSAYGCSKAALNHFAMDIASEEPSDKV 180

  Fly   179 RVNSVNPGVIITELQR-------RGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFL 232
            |...:.|||:.|::|:       ..|:..:|..:|.:..|.:..|    :.|..||.:|.|
Yeast   181 RAVCIAPGVVDTQMQKDIRETLGPQGMTPKALERFTQLYKTSSLL----DPKVPAAVLAQL 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	79/256 (31%)
IRC24	NP_012302.3	SPR-like_SDR_c	4..255	CDD:187625	78/255 (31%)