Protein Alignment CG12171 and NRE1

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_012301.3
• Gene: NRE1 / 854853
• SGDID: S000001474
• Length: 254
• Species: Saccharomyces cerevisiae
• Alignment Length: 200
• Identity: 67/200 - (33%)
• Similarity: 99/200 - (49%)
• Gaps: 29/200 - (14%)

  Fly     7 KVIIVTGASSGIGAG-TSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPA-----------L 59
            |||:|||.|.|||.. ..||.            :|||  :|....||...||.           .
Yeast     3 KVILVTGVSRGIGKSIVDVLF------------SLDK--DTVVYGVARSEAPLKKLKEKYGDRFF 53

  Fly    60 QVAADINSESDVQGIVSATLAKHGRIDVLVNNAGILE-LGSIENTSLEQFDRVMNTNVRSLYQLT 123
            .|..||..:|.::.:|:|.:..||:||.||.|||:|| :.::....:..:.::.:.|..|:..|.
Yeast    54 YVVGDITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLV 118

  Fly   124 HLVTPELIKTKGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVI 188
            .:..|||.||.||:|.|||......|....||..||||::.|...:|.|  .:.|:..:|.||::
Yeast   119 GIALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVAPGIV 181

  Fly   189 ITELQ 193
            .|::|
Yeast   182 DTDMQ 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	66/199 (33%)
NRE1	NP_012301.3	SPR-like_SDR_c	4..246	CDD:187625	65/198 (33%)