Protein Alignment CG12171 and CBR4

DIOPT Version :9

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: XP_006714454.1
• Gene: CBR4 / 84869
• HGNCID: 25891
• Length: 247
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 88/257 - (34%)
• Similarity: 124/257 - (48%)
• Gaps: 28/257 - (10%)

  Fly     6 DKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESD 70
            |||..|.|.|.|||...:.|:|:.|..|.::.|||:.....|..:    |...|..:.|:..|.|
Human     2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL----GGDHLAFSCDVAKEHD 62

  Fly    71 VQGIVSATLAKH-GRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTK 134
            ||.... .|.|| ||::.|||.|||...|.:..|..|.....::||:.............:|:.:
Human    63 VQNTFE-ELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ 126

  Fly   135 -GNIVNVS----------SVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVI 188
             |:||||.          |:.|::...|...|:.||..:..|:|.:|.|:|.|.:|||.|.||.:
Human   127 GGSIVNVGHRREMLLHKRSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFV 191

  Fly   189 ITELQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250
            .|::.:    |.:.     ||.|....|||.||..|||.|:.||.  |:.:.||..|.||||
Human   192 HTDMTK----DLKE-----EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	88/257 (34%)
		NADB_Rossmann	4..254	CDD:304358	88/257 (34%)
CBR4	XP_006714454.1	NADB_Rossmann	3..243	CDD:304358	87/256 (34%)
		3oxo_ACP_reduc	7..243	CDD:273824	85/252 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940