DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12171 and HSDL1

DIOPT Version :9

Sequence 1:NP_649563.1 Gene:CG12171 / 40690 FlyBaseID:FBgn0037354 Length:257 Species:Drosophila melanogaster
Sequence 2:NP_113651.4 Gene:HSDL1 / 83693 HGNCID:16475 Length:330 Species:Homo sapiens


Alignment Length:187 Identity:55/187 - (29%)
Similarity:96/187 - (51%) Gaps:6/187 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 IVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESDVQGI 74
            :|:||:.|||...:..||..|..:.::.||.:||...|:.|..........:.||.:|..::...
Human    71 VVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLP 135

  Fly    75 VSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDR---VMNTNVRSLYQLTHLVTPELI-KTKG 135
            :...| |...:.:||||.|:........|.|.: |:   ::|.|:.:...:.|:|.|.:: :.||
Human   136 IREAL-KDKDVGILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKG 198

  Fly   136 NIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITEL 192
            .||.:||.:..:..|.:.|::.|||.:|.|:|.:..|.|.||:.|.|:.|..:.|.:
Human   199 AIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12171NP_649563.1 fabG 2..251 CDD:235975 55/187 (29%)
NADB_Rossmann 4..254 CDD:304358 55/187 (29%)
HSDL1NP_113651.4 Required for mitochondria translocation 2..82 6/10 (60%)
17beta-HSD1_like_SDR_c 67..309 CDD:187614 55/187 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D913128at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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