DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12171 and MGC147226

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	XP_012816817.1	Gene:	MGC147226 / 780086	XenbaseID:	XB-GENE-5822220	Length:	521	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	79/248 - (31%)
Similarity:	132/248 - (53%)	Gaps:	9/248 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESDV 71
            :|..|||...|||...:..|.:.|..:.:|...|:|....|.:: ...|..::.:||||:.|.||
Frog   277 RVAYVTGGGQGIGRAFAHALGEAGAKVAVVDLMLEKAEAVAFEL-QVKGIKSVAIAADISKEEDV 340

  Fly    72 QGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELI-KTKG 135
            :.||...:...||||:..|||||....:.|:|:||::|:..:.|:|.|:.........:: :..|
Frog   341 KRIVDTIVTNWGRIDIACNNAGINMNSASEDTTLEEWDKTFSVNLRGLFMCCQAAGRVMLSQGYG 405

  Fly   136 NIVNVSSVNG-IRSFP-GVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQRRGGL 198
            .|:|.:|:.. |...| ..||||.|||.|.:.|:.:..|...:|||||.::||::.|.|     :
Frog   406 KIINTASMASLIVPHPQKQLAYNTSKAGVVKLTQTLGTEWIDRGVRVNCISPGIVDTPL-----I 465

  Fly   199 DQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGGR 251
            ..:|....::........||..:|.::.|.:.||||:.:.:.||.:|.::||:
Frog   466 HSDALKPLVQRWLNDIPAGRLAQVTDLQAGVVFLASEASDYMTGHNLVIEGGQ 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	78/246 (32%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	79/248 (32%)
MGC147226	XP_012816817.1	AdoMet_MTases	78..241	CDD:388410
MGC147226	XP_012816817.1	NADB_Rossmann	269..518	CDD:389744	78/246 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910