DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12171 and Hsdl2

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_077217.2	Gene:	Hsdl2 / 72479	MGIID:	1919729	Length:	490	Species:	Mus musculus

Alignment Length:	191	Identity:	59/191 - (30%)
Similarity:	91/191 - (47%)	Gaps:	12/191 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDK-------LNETAEQIVAAGGAPALQVAADIN 66
            :.:||||.|||...::..||.|..:.|..:...|       :...||:|.||||. ||....|:.
Mouse    13 VFITGASRGIGKAIALKAAKDGANIVIAAKTTQKHPKLLGTIYTAAEEIEAAGGT-ALPCVVDVR 76

  Fly    67 SESDVQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELI 131
            .|..:...|...:.|.|.||:|||||..:.|.:..:|..::.|.:||.|.|..|..:....|.|.
Mouse    77 DEQQINSAVEKAVEKFGGIDILVNNASAISLTNTLDTPTKRVDLMMNVNTRGTYLTSKACIPFLK 141

  Fly   132 KTK-GNIVNVSSVNGIRS--FPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVII 189
            |:| |:|:|:|....:..  |....||.::|..:......:|.|...: :.||::.|...|
Mouse   142 KSKVGHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFRGE-IAVNALWPRTAI 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	59/191 (31%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	59/191 (31%)
Hsdl2	NP_077217.2	HSDL2_SDR_c	8..248	CDD:187663	59/191 (31%)
		adh_short	12..197	CDD:278532	57/185 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	282..370
		SCP2	390..483	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810