Protein Alignment CG12171 and Hsd17b14

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_001178040.1
• Gene: Hsd17b14 / 691018
• RGDID: 1588673
• Length: 270
• Species: Rattus norvegicus
• Alignment Length: 261
• Identity: 92/261 - (35%)
• Similarity: 131/261 - (50%)
• Gaps: 33/261 - (12%)

  Fly     4 FKDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIV-----AAGGAPALQ--- 60
            :..||::|||.|.||||             .||...:|    :..|:|     .|||....|
  Rat     7 YSGKVVVVTGGSRGIGA-------------AIVRAFVD----SGAQVVFCDKDEAGGRAVEQELL 54

  Fly    61 ----VAADINSESDVQGIVSATLAKHGRIDVLVNNAGILELGSI-ENTSLEQFDRVMNTNVRSLY 120
                :..|:..|.|:|.::|.|:::.|.:|.:|||||......: |.||.:.|.:::..|:...|
  Rat    55 GTVFIPGDVTQEGDLQTLISETVSRFGHLDCVVNNAGYHPPAQLPEETSAQGFRQLLEENLLGAY 119

  Fly   121 QLTHLVTPELIKTKGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNP 185
            .|..|..|.|.|:||||:|:||:.|.......|.|..:|.||...|:.:||:.:..|||||.::|
  Rat   120 TLIKLALPHLRKSKGNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRYGVRVNCISP 184

  Fly   186 GVIITEL-QRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDG 249
            |.|.|.| |.......:.....|| ..:...|||.|:..||.||..|||| ||:|.||:.|.:.|
  Rat   185 GNIWTPLWQELAAATSDPRATILE-GTLAQPLGRMGQPAEVGAAAVFLAS-EATFCTGLELFMTG 247

  Fly   250 G 250
            |
  Rat   248 G 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	92/261 (35%)
Hsd17b14	NP_001178040.1	Rossmann-fold NAD(P)(+)-binding proteins	1..256	CDD:473865	92/261 (35%)