Protein Alignment CG12171 and Rdh8

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_001162065.1
• Gene: Rdh8 / 690953
• RGDID: 1589829
• Length: 312
• Species: Rattus norvegicus
• Alignment Length: 198
• Identity: 65/198 - (32%)
• Similarity: 105/198 - (53%)
• Gaps: 24/198 - (12%)

  Fly     9 IIVTGASSGIGAGTSVLLA-----KLGGLLTIVGRNLDKLNETAEQIVAAGG---APALQVA-AD 64
            ::::|.|||||...:|.||     :...:.|:  |:|.|    .|.:.||.|   ...|.|| .|
  Rat     8 VLISGCSSGIGLELAVQLAHDPRQRYQVVATM--RDLGK----KEPLEAAAGEALGKTLSVAQLD 66

  Fly    65 INSESDVQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPE 129
            :.|:..|...:|.  .:.|::|:||||||:..:|.:|:.||.....|.|||.....:|...|.|.
  Rat    67 VCSDESVTNCLSH--IEGGQVDILVNNAGVGLVGPLEDLSLATMQNVFNTNFFGAVRLVKAVLPG 129

  Fly   130 LIKTK-GNIVNVSSVNGIRSFPGVL---AYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIIT 190
            :.:.: |:||.||||.|::   ||:   .|..||.|::.|...:|::|....:.::.|.||.:||
  Rat   130 MKRRRQGHIVVVSSVMGLQ---GVMFNDVYAASKFALEGFFESLAIQLRQFNIFISMVEPGPVIT 191

  Fly   191 ELQ 193
            :.:
  Rat   192 DFE 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	65/198 (33%)
Rdh8	NP_001162065.1	Rossmann-fold NAD(P)(+)-binding proteins	8..262	CDD:473865	65/198 (33%)