Protein Alignment CG12171 and hsd17b8

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_001005292.2
• Gene: hsd17b8 / 64815
• ZFINID: ZDB-GENE-010110-1
• Length: 256
• Species: Danio rerio
• Alignment Length: 249
• Identity: 80/249 - (32%)
• Similarity: 125/249 - (50%)
• Gaps: 11/249 - (4%)

  Fly     7 KVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAA-GGAPALQVAADINSESD 70
            ::.:|||..||||.......|..|..:.:..||.:..|:|.|.:... .|...:.:..|::|:..
Zfish    10 RLTLVTGGGSGIGRAVCQRFATEGASVVVADRNEESANQTLELLPREHRGQEHMALGVDVSSKDS 74

  Fly    71 VQGIVSATLAKHGR-IDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELI--- 131
            |:.:|::...::.: ..|.||.|||.:...|.....:.||:|:..|::..:.:|..|:..|:
Zfish    75 VEKLVTSIQRRYFQPPSVCVNAAGITQDEFILKMEEDDFDKVIKVNLKGTFLVTQAVSKALVSAG 139

  Fly   132 KTKGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQRRG 196
            ..||:|:.|.|:.|.....|.:.|..|||.|...||..|.||:..|:|.|.|.||.|.|.
Zfish   140 SAKGSIITVGSIVGKVGNIGQVNYASSKAGVQGLTRTAAKELSKFGIRCNCVLPGFITTP----- 199

  Fly   197 GLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250
             :..:...|.::.......|||.||..|||.|.||||||::.:.||:|:.|.||
Zfish   200 -MTDKVPEKVIDKITSIIPLGRMGEPAEVADACAFLASDDSRYITGVSIEVAGG 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	80/249 (32%)
hsd17b8	NP_001005292.2	BKR_SDR_c	10..254	CDD:187594	80/249 (32%)