DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12171 and Decr2

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_741993.1	Gene:	Decr2 / 64461	RGDID:	71002	Length:	292	Species:	Rattus norvegicus

Alignment Length:	255	Identity:	83/255 - (32%)
Similarity:	133/255 - (52%)	Gaps:	8/255 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSES 69
            :|||..:||..||||...:.:..:.|....||.|:|.:::|.|:::|||.|...|.::.|:....
  Rat    27 QDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVSRSLPRVSEAAKKLVAATGKRCLPLSMDVRVPP 91

  Fly    70 DVQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTK 134
            .|...|...|.:.|:||:|:|.|....|......|...|..|::.:....:.::.::..:..:..
  Rat    92 AVMAAVDQALKEFGKIDILINCAAGNFLCPASALSFNAFKTVVDIDTLGTFNVSRVLYEKFFRDH 156

  Fly   135 GN-IVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVII-TE-LQRRG 196
            |. |||:::...:|.....|....:|||||..||.:|:|..|:.:||||:.||.|. || |:|.|
  Rat   157 GGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEWGPQNIRVNSLAPGAISGTEGLRRLG 221

  Fly   197 GLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGGRHAMCP 256
            |....:..|:|     :..:.|.|...|:|.::.:|||..||:.:||.|.||||.....|
  Rat   222 GPKASSKFKYL-----SSPIPRLGTKTEIAHSVLYLASPLASYVSGIVLVVDGGSWMTLP 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	81/248 (33%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	82/251 (33%)
Decr2	NP_741993.1	TER_DECR_SDR_a	26..273	CDD:187627	82/250 (33%)
		Substrate binding. /evidence=ECO:0000250	126..128		1/1 (100%)
		Microbody targeting signal	290..292
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810