Protein Alignment CG12171 and BDH2

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: XP_006714337.1
• Gene: BDH2 / 56898
• HGNCID: 32389
• Length: 259
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 83/269 - (30%)
• Similarity: 128/269 - (47%)
• Gaps: 44/269 - (16%)

  Fly     7 KVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQV-AADINSESD 70
            ||||:|.|:.|||...::..|:.|..:.....|..||.|..:.       |.:|. ..|:..:..
Human     7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKY-------PGIQTRVLDVTKKKQ 64

  Fly    71 VQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTK- 134
            :....:..    .|:|||.|.||.:..|::.:...:.:|..||.||||:|.:.....|:::..|
Human    65 IDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKS 125

  Fly   135 GNIVNVSSVNGIRSFPGVLA------------------YNVSKAAVDQFTRCVALELAPKGVRVN 181
            |||:|:|||   .|...|:|                  |:.:||||...|:.||.:...:|:|.|
Human   126 GNIINMSSV---ASSVKVMATDDEKLRLPMLRVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 187

  Fly   182 SVNPGVIIT-----ELQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFST 241
            .|.||.:.|     .:|.||. .:||...||:..|.    ||....:|:|....:|||||:::.|
Human   188 CVCPGTVDTPSLQERIQARGN-PEEARNDFLKRQKT----GRFATAEEIAMLCVYLASDESAYVT 247

  Fly   242 GISLPVDGG 250
            |..:.:|||
Human   248 GNPVIIDGG 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	83/269 (31%)
BDH2	XP_006714337.1	DHRS6_like_SDR_c	5..259	CDD:187626	83/269 (31%)