Protein Alignment CG12171 and Dhrs1

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_081095.2
• Gene: Dhrs1 / 52585
• MGIID: 1196314
• Length: 313
• Species: Mus musculus
• Alignment Length: 203
• Identity: 74/203 - (36%)
• Similarity: 105/203 - (51%)
• Gaps: 23/203 - (11%)

  Fly     5 KDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSES 69
            |.:|.:|||||.|||.|.::.|.|.|..:.|.||:||.|..||::..:.||. .:.|..|.:.||
Mouse     6 KGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRATAQEAQSLGGR-CVPVVCDSSQES 69

  Fly    70 DVQGIV-SATLAKHGRIDVLVNN--AGILELGSIENTSLEQF--------DRVMNTNVRSLYQLT 123
            :|:.:. .....:.||:||||||  ||:   .:|.||:.:.|        |.:.|..:|..|..:
Mouse    70 EVKSLFEQVDREQKGRLDVLVNNAYAGV---QAILNTTNKSFWEVPASIWDDINNVGLRGHYLCS 131

  Fly   124 ----HLVTPELIKTKGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVN 184
                .|:.|   ..||.||.|||..|::....| .|.|.|||.|:.....|.||...||...|:.
Mouse   132 VYGARLMVP---AGKGLIVIVSSPGGLQHMFNV-PYGVGKAACDRLAADCAHELRRHGVSYVSLW 192

  Fly   185 PGVIITEL 192
            ||::.||:
Mouse   193 PGLVQTEM 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	74/203 (36%)
Dhrs1	NP_081095.2	DHRS1-like_SDR_c	5..271	CDD:187664	74/203 (36%)