Protein Alignment CG12171 and DCXR

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_057370.1
• Gene: DCXR / 51181
• HGNCID: 18985
• Length: 244
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 85/248 - (34%)
• Similarity: 120/248 - (48%)
• Gaps: 23/248 - (9%)

  Fly     9 IIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQ-VAADINSESDVQ 72
            ::||||..|||.||...|...|..:..|.|....|:....:      .|.:: |..|:
Human    10 VLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRE------CPGIEPVCVDL------- 61

  Fly    73 GIVSAT---LAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIK-- 132
            |...||   |...|.:|:|||||.:..|......:.|.|||....|:|::.|::.:|...||.
Human    62 GDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARG 126

  Fly   133 TKGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQRRGG 197
            ..|.||||||....|:......|..:|.|:|..|:.:||||.|..:|||:|||.|::|.:.:...
Human   127 VPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATW 191

  Fly   198 LDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250
            .|.......|...    .||:..||:.|..||.||.||.:..:||.:|||:||
Human   192 SDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	85/248 (34%)
DCXR	NP_057370.1	XR_like_SDR_c	1..244	CDD:187609	85/248 (34%)