Protein Alignment CG12171 and HSD17B14

DIOPT Version :9

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_057330.2
• Gene: HSD17B14 / 51171
• HGNCID: 23238
• Length: 270
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 92/251 - (36%)
• Similarity: 134/251 - (53%)
• Gaps: 13/251 - (5%)

  Fly     4 FKDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSE 68
            :..||::|||...|||||........|..:.|    .|| :|:..:.:......|:.:..|:..|
Human     7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVI----CDK-DESGGRALEQELPGAVFILCDVTQE 66

  Fly    69 SDVQGIVSATLAKHGRIDVLVNNAGILELGS-IENTSLEQFDRVMNTNVRSLYQLTHLVTPELIK 132
            .||:.:||.|:.:.||:|.:|||||...... .|.||.:.|.:::..|:...|.||.|..|.|.|
Human    67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRK 131

  Fly   133 TKGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITEL-QRRG 196
            ::||::|:||:.|.......:.|..:|.||...|:.:||:.:|.|||||.::||.|.|.| :...
Human   132 SQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELA 196

  Fly   197 GL--DQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250
            .|  |..|.::   ...:...|||.|:..||.||..|||| ||:|.|||.|.|.||
Human   197 ALMPDPRATIR---EGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGG 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	92/251 (37%)
		NADB_Rossmann	4..254	CDD:304358	92/251 (37%)
HSD17B14	NP_057330.2	RDH_SDR_c	1..256	CDD:187638	92/251 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I5306
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4508
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487970at33208
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	1	1.000	-	-		X68
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.900