DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12171 and cbr4

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001007873.1	Gene:	cbr4 / 493259	XenbaseID:	XB-GENE-5935857	Length:	236	Species:	Xenopus tropicalis

Alignment Length:	245	Identity:	79/245 - (32%)
Similarity:	125/245 - (51%)	Gaps:	17/245 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESDV 71
            ||..|.|.|.|||...|.|||:....:.::.|:|    |.|:...|..|| .|.::.|::.|:::
Frog     3 KVCAVFGGSRGIGKAVSKLLAQRDYKVAVISRDL----EVAKAAAAEVGA-HLALSCDVSKENEI 62

  Fly    72 QGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTKGN 136
            |..........|.:|.|||:|||.....:..|..|....:::.|:....|...|....:|:.:|.
Frog    63 QDTFKEITNNLGNVDYLVNSAGIRRDALLLRTRSEDIRSLLSVNLVGTIQTCKLALRSMIQQQGG 127

  Fly   137 -IVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQRRGGLDQ 200
             |||:.|:.|.:...|...|..||..:..|::.:|.|:|.:.:|||.|.||.|.|::..  ||::
Frog   128 AIVNIGSIVGHKGNIGQSIYGASKEGLIGFSKSLAKEVAKRNIRVNVVAPGFIHTDMTL--GLEE 190

  Fly   201 EAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250
            ::..|.:       .|||.|:.:|||.::.||.  |:.:.||..|.||||
Frog   191 DSLTKMV-------PLGRFGDPEEVAQSVLFLL--ESPYITGHVLVVDGG 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	79/245 (32%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	79/245 (32%)
cbr4	NP_001007873.1	NADB_Rossmann	3..232	CDD:389744	79/245 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940