DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12171 and F12E12.11

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001040762.2	Gene:	F12E12.11 / 4363044	WormBaseID:	WBGene00044811	Length:	280	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	104/264 - (39%)
Similarity:	146/264 - (55%)	Gaps:	17/264 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSFKDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPA---LQVA 62
            |..|..||.:|||:|:|||...::|.|:.|..:||.|||.::|.|| .|.:...|.||   |.:|
Worm     1 MARFSGKVALVTGSSNGIGRAAALLFAQQGAKVTITGRNAERLEET-RQAILKSGVPAENVLAIA 64

  Fly    63 ADINSESDVQGIVSATLAKHGRIDVLVNNAGIL------ELGSIENTSLEQFDRVMNTNVRSLYQ 121
            ||:.::.....:::.||.|.||:|:||||||..      .:|.  :..:|.||:....|:||:..
Worm    65 ADLATDQGQTDLINGTLQKFGRLDILVNNAGAAVNDPQGRMGI--DQQIEDFDKTFQINMRSVVT 127

  Fly   122 LTHLVTPELIKTKGNIVNVSSV-NGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNP 185
            |.......||||||.|:||||: .|..:.|.::.|.:||||:|||||..|:.|...|||||||:|
Worm   128 LVQKAKEHLIKTKGEIINVSSIGGGPHAQPDMMYYGMSKAALDQFTRSTAITLIQHGVRVNSVSP 192

  Fly   186 GVIITELQRRGGLDQ---EAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLAS-DEASFSTGISLP 246
            |.:.|......|...   |..:|:.|..|.....|...:..|:|..|||||. ..:|:..|.|:.
Worm   193 GGVYTGFGEAMGFPPGALEKIMKYFESHKECVPCGHMAQPIEIAQVIAFLADRTMSSYIIGQSII 257

  Fly   247 VDGG 250
            .|||
Worm   258 ADGG 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	103/263 (39%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	103/261 (39%)
F12E12.11	NP_001040762.2	fabG	3..261	CDD:235975	101/260 (39%)
F12E12.11	NP_001040762.2	NADB_Rossmann	4..265	CDD:304358	103/261 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45843
OrthoDB	1	1.010	-	-		D487970at33208
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	1	1.000	-	-		X68
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.860