Protein Alignment CG12171 and dhrs4

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_956861.2
• Gene: dhrs4 / 393539
• ZFINID: ZDB-GENE-040426-1498
• Length: 276
• Species: Danio rerio
• Alignment Length: 257
• Identity: 83/257 - (32%)
• Similarity: 141/257 - (54%)
• Gaps: 23/257 - (8%)

  Fly     7 KVIIVTGASSGIGAGTSVLLAKLGGLLTIVGR---NLDKLNETAEQIVAAGGAPALQVAADINSE 68
            ||.|||.::.|||...:..|.:.|..:.:..|   |:||    |..::.:.....:....::...
Zfish    31 KVAIVTASTDGIGLAAAEALGQRGAHVVVSSRRQTNVDK----AVSLLRSKNIKVIGTTCNVGKA 91

  Fly    69 SDVQGIVSATLAKHGRIDVLVNNAGILE-LGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIK 132
            .|.:.:::.|:.:.|.:|:||:||.:.. .|:|.:::.|.:|:::..||::.:.||.:|.|.:.|
Zfish    92 EDREKLINMTVEQCGGVDILVSNAAVNPFFGNILDSTEEVWDKILGVNVKASFLLTKMVVPHIEK 156

  Fly   133 T-KGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITEL---- 192
            . .|::|.||||.|.:..|.:..|:|||.|:...||.:|.|||...:|||.|.||:|.|..
Zfish   157 RGGGSVVIVSSVAGYQPMPALGPYSVSKTALLGLTRALAPELAQSNIRVNCVAPGIIKTRFSSAL 221

  Fly   193 -QRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGGRHA 253
             :..|.|::     ||:...:.. ||:|   :|:...||||.|||||:.||.::.|.||.::
Zfish   222 WENEGVLEE-----FLKQTSIKR-LGQP---EEIGGVIAFLCSDEASYITGETITVTGGMNS 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	83/257 (32%)
dhrs4	NP_956861.2	CR_SDR_c	21..276	CDD:187641	83/257 (32%)