DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12171 and hsdl2

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_955893.1	Gene:	hsdl2 / 322347	ZFINID:	ZDB-GENE-030131-1066	Length:	415	Species:	Danio rerio

Alignment Length:	248	Identity:	73/248 - (29%)
Similarity:	116/248 - (46%)	Gaps:	34/248 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLD---KLNET----AEQIVAAGGAPALQVAADIN 66
            |.:||||.|||...::..|:.|..:.|..:..|   ||..|    |.:|.|||| .||....|:.
Zfish    13 IFITGASRGIGKAIALKAAQDGANVVIAAKTADPHPKLPGTIYTAAAEIEAAGG-KALPCIVDVR 76

  Fly    67 SESDVQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELI 131
            .|..:...|...:.|.|.||:|||||..:.|.....|.:::.|.::..|:|..|..:.|..|.|:
Zfish    77 DEKQINDAVEQAVEKFGGIDILVNNASAINLTGTLQTPMKKADLMLGINLRGTYLTSKLCIPHLL 141

  Fly   132 KTKG-NIVNVS---SVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPK---GVRVNSVNPGVII 189
            |:|. :|:|:|   ::|.| .|....||.::|..:   :.|| |.:|.:   .:.||::.|...|
Zfish   142 KSKNPHILNLSPPLNLNPI-WFKNHTAYTIAKYGM---SMCV-LGMAEEFRGSIAVNALWPKTAI 201

  Fly   190 TELQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTG 242
                      |.|.:..|..::|    |:.....|:.|..|:....:.:..||
Zfish   202 ----------QTAAMDMLGGSEV----GKQCRKVEIMADAAYAIFKQPTSFTG 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	73/248 (29%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	73/248 (29%)
hsdl2	NP_955893.1	HSDL2_SDR_c	8..248	CDD:187663	73/248 (29%)
		adh_short	12..210	CDD:278532	65/212 (31%)
		SCP2	311..408	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810