Protein Alignment CG12171 and rdh8a

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_957001.1
• Gene: rdh8a / 280648
• ZFINID: ZDB-GENE-021115-3
• Length: 318
• Species: Danio rerio
• Alignment Length: 230
• Identity: 73/230 - (31%)
• Similarity: 121/230 - (52%)
• Gaps: 33/230 - (14%)

  Fly     7 KVIIVTGASSGIGAGTSVLLA-----KLGGLLTIVGRNLDKLNETAEQIVAAG---GAPALQVAA 63
            ||:::||.|||||...:||||     :...:.|:  |:|.|.:...|   |||   |.....:..
Zfish     8 KVVLITGCSSGIGLRIAVLLARDEQKRYHVIATM--RDLKKKDRLVE---AAGEVYGQTLTLLPL 67

  Fly    64 DINSESDVQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTP 128
            ||.|:..|:..|::...:|  ||||:||||:..||.:|:.|:::..||..||.....::...|.|
Zfish    68 DICSDESVRQCVNSVKDRH--IDVLINNAGVGLLGPVESISMDEMKRVFETNFFGTVRMIKEVMP 130

  Fly   129 ELIKTK-GNIVNVSSVNGIRSFPGVL---AYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVII 189
            ::.|.: |:|:.:|||.|::   ||:   .|..||.|::.|...:|::|....|:::.:.||.:.
Zfish   131 DMKKRQAGHIIIMSSVMGLQ---GVVFNDVYTASKFAIEGFCESMAVQLLKFNVKLSLIEPGPVH 192

  Fly   190 TELQRRGGLDQEAYVKFLEH-AKVTHALGRPGEVK 223
            ||.:          .|.:|. ||:.:....|..|:
Zfish   193 TEFE----------TKMMEEVAKMEYPGADPDTVR 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	73/230 (32%)
rdh8a	NP_957001.1	type1_17beta-HSD-like_SDR_c	8..265	CDD:187666	73/230 (32%)