DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12171 and Dhrs4

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_695227.2	Gene:	Dhrs4 / 266686	RGDID:	708482	Length:	279	Species:	Rattus norvegicus

Alignment Length:	255	Identity:	80/255 - (31%)
Similarity:	130/255 - (50%)	Gaps:	23/255 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGR---NLDKLNETAEQIVAAGGAPALQVAADINS 67
            :||.:||.::.|||...:..||:.|..:.|..|   |:|:...|.:    ..|.....|...:..
  Rat    33 NKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQ----GEGLSVTGVVCHVGK 93

  Fly    68 ESDVQGIVSATLAKHGRIDVLVNNAGILE-LGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELI 131
            ..|.:.:|:..|..|..||:||:||.:.. .|::.:.:.|.:::|::.||.:...:...|.|.:.
  Rat    94 AEDREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMIKAVVPAME 158

  Fly   132 KT-KGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQRR 195
            |. .|::|.||||.|...||.:..|||||.|:...|:..|.|||||.:|||.:.||:|.|..
  Rat   159 KRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLIKTHF--- 220

  Fly   196 GGLDQEAYVKFLEHA-----KVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250
                  :.|.:.|.|     |.|..:.|.|:.::....::||.|::||:..|.::.|.||
  Rat   221 ------SSVLWKEKAREEMIKETMQIRRLGKPEDCVGIVSFLCSEDASYINGETVVVGGG 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	80/255 (31%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	80/255 (31%)
Dhrs4	NP_695227.2	CR_SDR_c	24..279	CDD:187641	80/255 (31%)
Dhrs4	NP_695227.2	Microbody targeting signal	277..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334275
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740