Protein Alignment CG12171 and Hsd17b1

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_036983.1
• Gene: Hsd17b1 / 25322
• RGDID: 2836
• Length: 344
• Species: Rattus norvegicus
• Alignment Length: 278
• Identity: 75/278 - (26%)
• Similarity: 113/278 - (40%)
• Gaps: 58/278 - (20%)

  Fly     8 VIIVTGASSGIGAGTSVLLA-------KLGGLLTIVGRNLDKLNETAEQIVAAGGAP-ALQVAAD 64
            |:::||.|||||...:|.||       |:...|    |:|.......|...|.|..| :|::.
  Rat     5 VVLITGCSSGIGLHLAVRLASDRSQSFKVYATL----RDLKSQGPLLEAARAQGCPPGSLEIL-- 63

  Fly    65 INSESDVQGIVSATLAK----HGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHL 125
               |.||:...|...|:    .||:||||.|||....|.:|...|.....|::.||....::...
  Rat    64 ---ELDVRDSESVAAARACVTEGRVDVLVCNAGRGLFGPLEAHELNAVGAVLDVNVLGTIRMLQA 125

  Fly   126 VTPELIKT-KGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVII 189
            ..|::.:. .|.::..:||.|:...|....|..||.|::.....:|:.|...||.|:.:..|.:.
  Rat   126 FLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAILLPLFGVHVSLIECGAVH 190

  Fly   190 TELQRR------GGLD-------------QEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASD 235
            |....:      |.|:             |..|.:.|..|:      .|.||.|:     ||.:.
  Rat   191 TAFHEKLEGGPGGALERADAQTRHLFAHYQRGYEQALSEAQ------DPEEVTEL-----FLTAM 244

  Fly   236 EAS------FSTGISLPV 247
            .|.      |||...||:
  Rat   245 RAPQPALRYFSTNRFLPL 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	75/278 (27%)
Hsd17b1	NP_036983.1	Rossmann-fold NAD(P)(+)-binding proteins	4..260	CDD:473865	73/274 (27%)