Protein Alignment CG12171 and Rdh8

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_001025461.1
• Gene: Rdh8 / 235033
• MGIID: 2685028
• Length: 317
• Species: Mus musculus
• Alignment Length: 201
• Identity: 63/201 - (31%)
• Similarity: 104/201 - (51%)
• Gaps: 22/201 - (10%)

  Fly     5 KDKVIIVTGASSGIGAGTSVLLA-----KLGGLLTIVGRNLDKLNETAEQIVAAG---GAPALQV 61
            :.:.::::|.|||||...::.||     :...:.|:  |:|.| .|..|  .|||   |.....|
Mouse     4 QQRTVLISGCSSGIGLELALQLAHDPRQRYQVVATM--RDLGK-KEPLE--AAAGEALGKTLSVV 63

  Fly    62 AADINSESDVQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLV 126
            ..|:.::..|...:|.  .:.|::||||||||:..:|.:|..||.....|.|||.....:|...|
Mouse    64 QLDVCNDESVTDCLSH--IEGGQVDVLVNNAGVGLVGPLEGLSLATMQSVFNTNFFGAVRLVKAV 126

  Fly   127 TPELIKTK-GNIVNVSSVNGIRSFPGVL---AYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGV 187
            .|.:.:.: |:||.||||.|::   ||:   .|..||.|::.|...:|::|....:.::.|.||.
Mouse   127 LPGMKRRRQGHIVVVSSVMGLQ---GVMFNDVYAASKFALEGFFESLAIQLRQFNIFISMVEPGP 188

  Fly   188 IITELQ 193
            :.|:.:
Mouse   189 VTTDFE 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	63/201 (31%)
Rdh8	NP_001025461.1	Rossmann-fold NAD(P)(+)-binding proteins	6..263	CDD:473865	63/199 (32%)