Protein Alignment CG12171 and Cbr4

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_663570.2
• Gene: Cbr4 / 234309
• MGIID: 2384567
• Length: 236
• Species: Mus musculus
• Alignment Length: 246
• Identity: 90/246 - (36%)
• Similarity: 124/246 - (50%)
• Gaps: 17/246 - (6%)

  Fly     6 DKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESD 70
            |||..|.|.|.|||...:.|:|:.|..|.||.|||:....||.::    |...|....|:..|.|
Mouse     2 DKVCAVFGGSRGIGRAVAQLMAQKGYRLAIVSRNLEVAKVTAGEL----GGNHLAFRCDVAKEQD 62

  Fly    71 VQGIVSATLAKH-GRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTK 134
            ||.... .:.|| |.::.|||.|||.....:..|..|.....::||:.............:|:..
Mouse    63 VQSTFQ-EMEKHLGPVNFLVNAAGINRDSLLVRTKTEDMISQLHTNLLGSMLTCKAAMKTMIQQG 126

  Fly   135 GNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQRRGGLD 199
            |:||||.|:.|::...|..||:.:|..:..|:|.:|.|:|.|.:|||.|.||.|.|::.|
Mouse   127 GSIVNVGSIIGLKGNVGQSAYSATKGGLVGFSRSLAKEVARKKIRVNVVAPGFIRTDMTR----- 186

  Fly   200 QEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250
               ::| .||.|....|||.||..|||.|:.||.  |:.:.||..|.||||
Mouse   187 ---HLK-EEHFKKNIPLGRFGETLEVAHAVVFLL--ESPYITGHVLIVDGG 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	90/246 (37%)
Cbr4	NP_663570.2	Rossmann-fold NAD(P)(+)-binding proteins	3..232	CDD:473865	89/245 (36%)