DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12171 and F28H7.2

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_505742.1	Gene:	F28H7.2 / 185096	WormBaseID:	WBGene00009236	Length:	284	Species:	Caenorhabditis elegans

Alignment Length:	274	Identity:	103/274 - (37%)
Similarity:	151/274 - (55%)	Gaps:	36/274 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSFKDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAP---ALQVA 62
            |..|.|||.|:||:|:|||..|:.|||..|..:|:.|||.::|.|| :.|:...|.|   .|.|.
Worm     1 MSRFTDKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEET-KNILLGAGVPEGNVLVVV 64

  Fly    63 ADINSESDVQGIVSATLAKHGRIDVLVNNAGI----LELGSIENTSLEQFDRVMNTNVRSLYQLT 123
            .||..||..:.::.:||.|.|:||:||||||.    .:..|..|.|::.:.:....||:|:.::|
Worm    65 GDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQSVIEMT 129

  Fly   124 HLVTPELIKTKGNIVNVSSVNGIRSFPGVLA------YNVSKAAVDQFTRCVALELAPKGVRVNS 182
            ....|.|.||:|.|||:||:..     |..|      |:::|||:||:||..|::|.|:|:||||
Worm   130 QKARPHLAKTQGEIVNISSIGA-----GPAAQVASPYYSIAKAALDQYTRTAAIDLVPEGIRVNS 189

  Fly   183 VNPGVIITELQR-RGGLDQEAYVKFLEHAKVTHALGRPGEV---------KEVAAAIAFLASDEA 237
            |:||.:.|.... ..||.:|....|.::      ||...|.         :::|..|||||...|
Worm   190 VSPGAVSTGFSAVSRGLTEEKSKAFYDY------LGAQRECIPRGFCAVPEDIAKVIAFLADRNA 248

  Fly   238 S-FSTGISLPVDGG 250
            | :..|.::..|||
Worm   249 SNYIIGQTIVADGG 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	102/273 (37%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	102/271 (38%)
F28H7.2	NP_505742.1	fabG	3..262	CDD:235506	100/270 (37%)
F28H7.2	NP_505742.1	NADB_Rossmann	4..266	CDD:304358	102/271 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45843
OrthoDB	1	1.010	-	-		D487970at33208
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X68
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.830