Protein Alignment CG12171 and D1054.8

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_505755.1
• Gene: D1054.8 / 183917
• WormBaseID: WBGene00008375
• Length: 278
• Species: Caenorhabditis elegans
• Alignment Length: 264
• Identity: 105/264 - (39%)
• Similarity: 159/264 - (60%)
• Gaps: 17/264 - (6%)

  Fly     1 MPSFKDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAP--ALQVAA 63
            |..|.:||.|:||:|:|||..|:||.|:.|..:||.||:.::|.||.:||:|||.:.  ...|.|
 Worm     1 MTRFAEKVAIITGSSNGIGRATAVLFAREGAKVTITGRHAERLEETRQQILAAGVSEQNVNSVVA 65

  Fly    64 DINSESDVQGIVSATLAKHGRIDVLVNNAGILELGSIENT----SLEQFDRVMNTNVRSLYQLTH 124
            |:.:::....|:|.||.|.|::|:||||||.....|...|    |:|.:|..:|.|:||:..||.
 Worm    66 DVTTDAGQDEILSTTLGKFGKLDILVNNAGAAIPDSQSKTGTAQSIESYDATLNLNLRSVIALTK 130

  Fly   125 LVTPELIKTKGNIVNVSSV-NGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVI 188
            ...|.|..|||.|||:||: :|:.:.|....|:::|||:||:||..|::|...|:||||::||::
 Worm   131 KAVPHLSSTKGEIVNISSIASGLHATPDFPYYSIAKAAIDQYTRNTAIDLIQHGIRVNSISPGLV 195

  Fly   189 ITELQRRGGLDQEAYVKF------LEHAKVTHALGRPGEVKEVAAAIAFLASDE-ASFSTGISLP 246
            .|......|:.:|...||      ::.......:|:|.::.||   |||||..: :|:..|..|.
 Worm   196 ATGFGSAMGMPEETSKKFYSTMATMKECVPAGVMGQPQDIAEV---IAFLADRKTSSYIIGHQLV 257

  Fly   247 VDGG 250
            ||||
 Worm   258 VDGG 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	104/261 (40%)
D1054.8	NP_505755.1	SDR_c11	4..265	CDD:187622	104/261 (40%)