DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12171 and C06E4.6

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_501154.1	Gene:	C06E4.6 / 182329	WormBaseID:	WBGene00015535	Length:	274	Species:	Caenorhabditis elegans

Alignment Length:	262	Identity:	96/262 - (36%)
Similarity:	148/262 - (56%)	Gaps:	12/262 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSFKDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAG--GAPALQVAA 63
            |..|.|||.|:||:|:|||..|:||||..|..:||.||:..:|.||.:.|:.||  ......|.|
Worm     1 MARFTDKVAIITGSSNGIGRATAVLLATDGAKVTITGRDAARLEETRQAILKAGISATNVNSVVA 65

  Fly    64 DINSESDVQGIVSATLAKHGRIDVLVNNAGILELGSIENT----SLEQFDRVMNTNVRSLYQLTH 124
            |:.:......::|:||.|.|:|::|:||||.....|...|    |:|...::...|::|:.::..
Worm    66 DVTTAEGQDLLISSTLDKFGKINILINNAGANIPDSQGQTRTKCSIENLTKMFQLNLQSVVEMVQ 130

  Fly   125 LVTPELIKTKGNIVNVSSVN-GIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVI 188
            .|.|.|.||:|.|||:||:. |..:.|....|:.:|||:||::||.|::|..:|:|:|.|.||.:
Worm   131 KVRPHLAKTRGEIVNISSIGAGPAAQPASPYYSSAKAALDQYSRCAAIDLISEGIRINVVQPGFV 195

  Fly   189 ITELQRRG-GLDQEAYVKFLE-HAKVTHAL--GRPGEVKEVAAAIAFLASDEAS-FSTGISLPVD 248
            .|...... ||..:..|||.: ...:.|.:  |..|:...:|:.||||...:.| :..|.::..|
Worm   196 STGFSTAARGLSADESVKFYDLMGSLPHCIPAGYCGQPDHLASVIAFLVDRKVSEYIVGQTIIAD 260

  Fly   249 GG 250
            ||
Worm   261 GG 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	95/261 (36%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	95/259 (37%)
C06E4.6	NP_501154.1	FabG	3..262	CDD:223959	93/258 (36%)
C06E4.6	NP_501154.1	NADB_Rossmann	4..266	CDD:304358	95/259 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45843
OrthoDB	1	1.010	-	-		D487970at33208
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X68
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.830