Protein Alignment CG12171 and dhrs-4

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_506230.1
• Gene: dhrs-4 / 179772
• WormBaseID: WBGene00010063
• Length: 260
• Species: Caenorhabditis elegans
• Alignment Length: 262
• Identity: 93/262 - (35%)
• Similarity: 140/262 - (53%)
• Gaps: 13/262 - (4%)

  Fly     1 MPS----FKDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQV 61
            |||    |:.||.|||.|:.|||...:..|...|..:.|..||...::|..|.:...|......:
 Worm     1 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGI 65

  Fly    62 AADINSESDVQGIVSATLAKHGRIDVLVNNAGI-LELGSIENTSLEQFDRVMNTNVRSLYQLTHL 125
            |..|.|..|.:.:|..||.|.|:|::||||.|| ...|.|...|.:.:|::...||::.:|:|.|
 Worm    66 AGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKL 130

  Fly   126 VTPELIKTKGN-IVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVII 189
            |.|.:.|..|. |:..:|.:..:|.||:.||.|:|..:...||.:|:.||...:|||.:.||||.
 Worm   131 VHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIK 195

  Fly   190 TELQR---RGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGGR 251
            |::.:   .||.|.|..:..::..    ||||.|...:.|..:|:||||::|:.||..:.:.||.
 Worm   196 TKMSQVLWDGGEDAEKELTDIQEI----ALGRLGVPDDCAGTVAYLASDDSSYITGEMIIIAGGV 256

  Fly   252 HA 253
            .|
 Worm   257 QA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	90/255 (35%)
dhrs-4	NP_506230.1	Rossmann-fold NAD(P)(+)-binding proteins	9..260	CDD:473865	89/254 (35%)