Protein Alignment CG12171 and dhs-9

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_498146.1
• Gene: dhs-9 / 175737
• WormBaseID: WBGene00000973
• Length: 319
• Species: Caenorhabditis elegans
• Alignment Length: 753
• Identity: 128/753 - (16%)
• Similarity: 223/753 - (29%)
• Gaps: 299/753 - (39%)

  Fly     1 MCSRFFGQKRSFSK-------------------------FLQISPQVKEALASGEG--------- 31
            |.|:|.|.:..|:|                         ...:..:::|...||..
 Worm   290 MASQFLGDESVFAKDDGDEVRRTAELDHEIKEMSRKKKELESVKEKIREHFESGANSSLNGTDMA 354

  Fly    32 ---------VVALESTVITHGLPYPHNLSTARSLEQKVR--SSGSHPATIALFDGKIHVGLD--- 82
                     |::|||.|           |:..:|.|::|  ::|.......|...|..:..|
 Worm   355 EKVDELVNKVISLESAV-----------SSQTALIQRLRNETNGLQTQISTLETDKALLADDKSD 408

  Fly    83 --------DEKLELLAS-SQNAVKVSSR------DIAKTLIKKEVGGTTVASTMKIAHAAGISVF 132
                    :|||:.|.. .:|.:..||.      |....|.....|..........:....||:.
 Worm   409 LRNKLKEMEEKLKALQDLDRNVLDKSSNLQTHFDDACHNLDNLSGGNLHEVKPESESDNLAISIE 473

  Fly   133 ATGGIGGVHRGADQTFDVSADL--------QELSQTPVCVVCSGVKSILDIPKTVEYLETHSVNC 189
            ....:.|..|    |.|:|.::        :|..:.||              |:|::.:|.:.
 Worm   474 PQKDLEGEKR----TLDISEEIKEHQKETGEEKKEAPV--------------KSVKFEQTRNA-- 518

  Fly   190 IVYGQENVFPSFFTRTSDRKAQFCTESLEEVVHLLKTSKSLGLPYGTILACPIPEKYAADGDAIQ 254
             ...:::..||....|       ..||.|:|...|:..                       ||..
 Worm   519 -TIAEDSTIPSTNPDT-------VLESTEKVDSDLEKQ-----------------------DASD 552

  Fly   255 KAIDQAVQEAIEQNIAS---QSVTPFILARVNELTQGASMATNIALLENNASIAGRLAAKLCDRR 316
            |. |..:...:|...||   .||...:|.:..|..:..|:.:|::..|::.|..|.
 Worm   553 KT-DSVLDNVLENQAASDQTDSVLDSVLEKQGESDKIDSVPSNVSEKESDISFNGE--------- 607

  Fly   317 PLTISQSQPTASTTRKPKVVSIGATIVDFEAITSEDVKDDGGSYNGQVVQRMG------------ 369
                                            ..||.|:..|..:.:.:...|
 Worm   608 --------------------------------QQEDQKEKEGEPDWKEMFMKGMENREKHLLTEY 640

  Fly   370 -GVARNHADALARLGCDSVFISAIGDDNNGHFFRQNSHKIDINRVKIISNKPTCTYLAVNVKGNV 433
             .:.||..|....|           |:.......:|:.|.|  .:|::..|
 Worm   641 TTILRNFKDMKKTL-----------DETKTKMKTENATKDD--EIKLLREK-------------- 678

  Fly   434 KYGIVTCEPLLSVITPSLVESNEDALESSDFILLDSNLSVPVMARVLEIAKKHDKQVWLEPTDID 498
                      :|::...|.:|| |.:|:.   |.:.:.|:..||              .|..::.
 Worm   679 ----------MSLLQKGLGDSN-DLMENQ---LSNDDYSIGFMA--------------AENQNMS 715

  Fly   499 KVKKVFDTGLVGAVTAASPNANEFLK-----WAKLCHV-----SVDPSVIDTADGVLELIEKEK- 552
            .|::.|..           |.:|.|:     |.:....     |.|.|:.|....:.:|.::.|
 Worm   716 LVEEQFRL-----------NIDELLEENLDFWLRFSTAFGQIQSYDTSIEDLQAEISKLEQRRKQ 769

  Fly   553 -----TKLLLNTSI--FIVTL----------ANKGSAVVYRNKLGQLEFQSL-PPPLQMNKVVSV 599
                 .|..|.:.:  ..|.|          ..||:|:  :.:| :..|:|| ....::.|.:..
 Worm   770 DGSSTAKYALRSDVRPLYVHLREINTDLGLWLEKGAAL--KEEL-KSRFESLCNIQDEITKALKS 831

  Fly   600 SGAGDSFN---------SGVIAGL-AHNKTVVESLQIG 627
            |...|.|.         .|.:..: ..|..|.:.||.|
 Worm   832 SAEDDDFRFTSYQAAKFQGEVLNMKQENNKVADELQAG 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	53/320 (17%)
dhs-9	NP_498146.1	Rossmann-fold NAD(P)(+)-binding proteins	3..276	CDD:473865