DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12171 and Y47G6A.22

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001021765.1	Gene:	Y47G6A.22 / 171925	WormBaseID:	WBGene00021647	Length:	254	Species:	Caenorhabditis elegans

Alignment Length:	252	Identity:	137/252 - (54%)
Similarity:	174/252 - (69%)	Gaps:	2/252 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGG--APALQVAADINSESD 70
            |.||||||||||...::|||:....|::.|||:..|||.|.|||:||.  ...|..|.::.||..
Worm     3 VAIVTGASSGIGRAAALLLARNNYKLSLTGRNVAALNELAGQIVSAGSDKNDVLVTAVELASEEA 67

  Fly    71 VQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTKG 135
            .:.||.||:.|.||||.|:|:||||..|.:.::.:|.:|.:||.|||||.:||....|.:|.|||
Worm    68 PKTIVDATVQKFGRIDTLINSAGILRAGPVLDSGIEVYDELMNVNVRSLIRLTRAALPHIITTKG 132

  Fly   136 NIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQRRGGLDQ 200
            .:|||||:||...||.|..|.:||:||||||:|:|||:||.|||||:|.|||.:|.|.|..|.|:
Worm   133 TVVNVSSINGPCPFPNVTYYCMSKSAVDQFTKCLALEMAPNGVRVNAVCPGVTVTNLHRTSGQDE 197

  Fly   201 EAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGGRHAMCPR 257
            ..|..|||.:|.||||||||:..|||.||.||||:::||:||..|.|||||..|.||
Worm   198 TTYSAFLERSKTTHALGRPGDANEVAEAIYFLASEKSSFTTGELLRVDGGRGIMHPR 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	132/244 (54%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	134/247 (54%)
Y47G6A.22	NP_001021765.1	NADB_Rossmann	3..251	CDD:304358	134/247 (54%)
Y47G6A.22	NP_001021765.1	fabG	3..247	CDD:235506	131/243 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	242	1.000	Domainoid score	I1236
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H133865
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1963
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45843
OrthoDB	1	1.010	-	-		D487970at33208
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	1	1.000	-	-		mtm4794
orthoMCL	1	0.900	-	-		OOG6_101836
Panther	1	1.100	-	-	O	PTHR43975
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	1	1.000	-	-		X68
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.910