DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12171 and Y47G6A.21

DIOPT Version :9

Sequence 1:	NP_649563.1	Gene:	CG12171 / 40690	FlyBaseID:	FBgn0037354	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001021764.1	Gene:	Y47G6A.21 / 171924	WormBaseID:	WBGene00021646	Length:	255	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	133/253 - (52%)
Similarity:	173/253 - (68%)	Gaps:	3/253 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPA---LQVAADINSES 69
            |.|:||||||||.||::|.||....|::.|||.|.|.|.|...::.|...|   |..|.:::|:.
Worm     3 VAIITGASSGIGKGTALLFAKKKYQLSLTGRNTDSLKEVAALCISEGAISADDILITAVELSSDE 67

  Fly    70 DVQGIVSATLAKHGRIDVLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTK 134
            ..:.||.||:.|.||||.|:|:||||..|.:.::.:|.:|.:||.|||||.:||....|.:|.||
Worm    68 APKAIVDATVQKFGRIDSLINSAGILRAGPVLDSGIEVYDELMNVNVRSLIRLTRAALPHIITTK 132

  Fly   135 GNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQRRGGLD 199
            |.:|||||:||...|.||..|.:||:||||||:|:|||:||.|||||:|.||||:|.:.|..|.|
Worm   133 GTVVNVSSINGPCPFAGVTYYCMSKSAVDQFTKCLALEMAPNGVRVNAVCPGVIVTNIHRASGQD 197

  Fly   200 QEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGGRHAMCPR 257
            :..|..|||.:|.||||||||...|||.||.||:|:::||:||..|.|||||..|.||
Worm   198 EATYAAFLEKSKTTHALGRPGTTSEVAEAILFLSSEKSSFTTGQLLKVDGGRGIMHPR 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	128/245 (52%)
CG12171	NP_649563.1	NADB_Rossmann	4..254	CDD:304358	130/248 (52%)
Y47G6A.21	NP_001021764.1	FabG	1..249	CDD:223959	128/245 (52%)
Y47G6A.21	NP_001021764.1	NADB_Rossmann	3..252	CDD:304358	130/248 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	242	1.000	Domainoid score	I1236
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H133865
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1963
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45843
OrthoDB	1	1.010	-	-		D487970at33208
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	1	1.000	-	-		mtm4794
orthoMCL	1	0.900	-	-		OOG6_101836
Panther	1	1.100	-	-	O	PTHR43975
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1710
SonicParanoid	1	1.000	-	-		X68
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.910