Protein Alignment CG12171 and Hsd17b8

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_038571.2
• Gene: Hsd17b8 / 14979
• MGIID: 95911
• Length: 259
• Species: Mus musculus
• Alignment Length: 259
• Identity: 80/259 - (30%)
• Similarity: 122/259 - (47%)
• Gaps: 23/259 - (8%)

  Fly     5 KDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSES 69
            :..:.:||||.||||...||.||..|.  .:...:||  ...|:..|...|:|..:..|.....:
Mouse     8 RSALALVTGAGSGIGRAISVRLAAEGA--AVAACDLD--GAAAQDTVRLLGSPGSEDGAPRGKHA 68

  Fly    70 DVQGIVSATLAKHGRID-----------VLVNNAGILELGSIENTSLEQFDRVMNTNVRSLYQLT 123
            ..|..||...|....::           |:|:.|||.....:.:.|.|.:|||:..|::..:.:|
Mouse    69 AFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDRVIAVNLKGTFLVT 133

  Fly   124 HLVTPELIKT--KGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPG 186
            ......|:.:  :|:|:|:||:.|.....|...|..|||.|...|:..|.||...|:|.|||.||
Mouse   134 QAAAQALVSSGGRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIRCNSVLPG 198

  Fly   187 VIITELQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDGG 250
            .|.|.      :.|:...|..:.......||..|:.::||..:|||||:::.:.||.|:.|.||
Mouse   199 FIATP------MTQKMPEKVKDKVTAMIPLGHMGDPEDVADVVAFLASEDSGYITGASVEVSGG 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	80/259 (31%)
Hsd17b8	NP_038571.2	Rossmann-fold NAD(P)(+)-binding proteins	11..258	CDD:473865	80/256 (31%)