Protein Alignment CG12171 and DHRS1

DIOPT Version :9

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_001129522.1
• Gene: DHRS1 / 115817
• HGNCID: 16445
• Length: 313
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 80/260 - (30%)
• Similarity: 118/260 - (45%)
• Gaps: 43/260 - (16%)

  Fly     7 KVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESDV 71
            :|.:|||||.|||.|.::.|.|.|..:.|.||:||.|...|::..:.|| ..:.|..|.:.||:|
Human     8 QVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGG-QCVPVVCDSSQESEV 71

  Fly    72 QGIV-SATLAKHGRIDVLVNN--AGILELGSIEN-----TSLEQFDRVMNTNVRSLYQLT----H 124
            :.:. .....:.||:||||||  ||:..:.:..|     |....:|.:.|..:|..|..:    .
Human    72 RSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGAR 136

  Fly   125 LVTPELIKTKGNIVNVSSVNGIRSFPGVL------AYNVSKAAVDQFTRCVALELAPKGVRVNSV 183
            |:.|   ..:|.||.:||       ||.|      .|.|.|||.|:.....|.||...||...|:
Human   137 LMVP---AGQGLIVVISS-------PGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSL 191

  Fly   184 NPGVIITELQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVD 248
            .||::.|||.:             ||......|..| .:|:..:|.:...:.|.|....::|..|
Human   192 WPGIVQTELLK-------------EHMAKEEVLQDP-VLKQFKSAFSSAETTELSGKCVVALATD 242

  Fly   249  248
            Human   243  242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	fabG	2..251	CDD:235975	80/260 (31%)
		NADB_Rossmann	4..254	CDD:304358	80/260 (31%)
DHRS1	NP_001129522.1	PRK08303	1..271	CDD:236229	80/260 (31%)
		DHRS1-like_SDR_c	5..271	CDD:187664	80/260 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2936
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.760