Protein Alignment CG12171 and DHRS2

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_878912.1
• Gene: DHRS2 / 10202
• HGNCID: 18349
• Length: 300
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 62/190 - (32%)
• Similarity: 103/190 - (54%)
• Gaps: 2/190 - (1%)

  Fly     6 DKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESD 70
            ::|.:|||::||||...:..||:.|..:.|..|....::....::...|.:.| .:...:....|
Human    36 NRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVA-GIVCHVGKAED 99

  Fly    71 VQGIVSATLAKHGRIDVLVNNAGILEL-GSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTK 134
            .:.:|:..|...|.:|.||.:||:..| ||...||.:.:|::::.||:|...|...:.|.:...:
Human   100 REQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRR 164

  Fly   135 GNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQR 194
            |.::.|||:........:..|||||.|:...||.:|||||||.:|||.|.||:|.|:..:
Human   165 GAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSK 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	62/190 (33%)
DHRS2	NP_878912.1	Rossmann-fold NAD(P)(+)-binding proteins	27..>226	CDD:473865	62/190 (33%)