Protein Alignment CG12171 and hsd17b14

DIOPT Version :10

• Sequence 1: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: XP_002935043.1
• Gene: hsd17b14 / 100498205
• XenbaseID: XB-GENE-986127
• Length: 276
• Species: Xenopus tropicalis
• Alignment Length: 261
• Identity: 79/261 - (30%)
• Similarity: 129/261 - (49%)
• Gaps: 29/261 - (11%)

  Fly     4 FKDKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSE 68
            ::|:|.::||.:.|||........|.|..:....::.: ......:|.|||....:.|..|:..|
 Frog    12 YRDRVAVITGGTKGIGEAMVKEFVKSGARVVFCSKDTE-AKALENEIKAAGPGDCIYVCCDVTKE 75

  Fly    69 SDVQGIVSATLAKHGRIDVLVNNAG-ILELGSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIK 132
            .|::.::..|:..:|:||.|:|||| .....:|:.||.:.|..::|.|:...:.......|.|.|
 Frog    76 EDIKKLIEITVMNYGQIDCLINNAGWHPPEQTIDGTSADDFRDLLNLNLIGYFLTAKYALPHLRK 140

  Fly   133 TKGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIIT------- 190
            |:|||:|:||:.||......:.|..:|.||...|:.:|::.:...||:||::||.|.|
 Frog   141 TQGNIINISSLVGIIGQKHAIPYVATKGAVTAMTKAMAVDESRHNVRINSISPGNIWTPLWEELS 205

  Fly   191 ------ELQRRGGLDQEAYVKFLEHAKVTHALGRPGEVKEVAAAIAFLASDEASFSTGISLPVDG 249
                  |...:||:|.:             .|||.|..:|.|.|..:||: |.:|.|||.|.:.|
 Frog   206 SHSKNSEAMIQGGIDAQ-------------LLGRMGTAEECAKAALYLAA-EGTFCTGIDLLLTG 256

  Fly   250 G 250
            |
 Frog   257 G 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	79/261 (30%)
hsd17b14	XP_002935043.1	Rossmann-fold NAD(P)(+)-binding proteins	6..265	CDD:473865	79/261 (30%)