Protein Alignment CG31549 and hcaB

DIOPT Version :10

• Sequence 1: NP_730972.2
• Gene: CG31549 / 40689
• FlyBaseID: FBgn0051549
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_417036.1
• Gene: hcaB / 945346
• ECOCYCID: G7335
• Length: 270
• Species: Escherichia coli
• Alignment Length: 281
• Identity: 70/281 - (24%)
• Similarity: 110/281 - (39%)
• Gaps: 47/281 - (16%)

  Fly     1 MSSFKDKVIIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKLKETADNIVAAGGATPLELQADM 65
            ||...::.|.:||..||:|.:......:.|..:..:..:..|:.......    |...|.::.::
E. coli     1 MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVASLRQRF----GEHILAVEGNV 61

  Fly    66 TKEAEVQQIVGATLAKHGRIDVLVNNAGI--------------LETGSIEATSLEQFDRLMNTNV 116
            |..|:.|:.|...|.:.|::|..:.||||              ||||         |..|.|.||
E. coli    62 TCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPAETLETG---------FHELFNVNV 117

  Fly   117 RSLYQLTMLATPELVKTKGNIVNVSSVCGLRAFPGVLAYNVSKAAVDQFTACIALELAPKGVRVN 181
            ...........|.|:.::|:::...|........|...|..||.|.......:|.||||| ||||
E. coli   118 LGYLLGAKACAPALIASEGSMIFTLSNAAWYPGGGGPLYTASKHAATGLIRQLAYELAPK-VRVN 181

  Fly   182 AVNPGVIVTDIHKRG----GMDEETYAKFLEHCKITHAL-----GRPGDVKEVAAAIAFLASDQA 237
            .|.|..:.:|:  ||    |..|.:..:.|...||...|     .:|.|.......:....:::|
E. coli   182 GVGPCGMASDL--RGPQALGQSETSIMQSLTPEKIAAILPLQFFPQPADFTGPYVMLTSRRNNRA 244

  Fly   238 SFTTGISLPVDGG------RH 252
              .:|:.:..|.|      ||
E. coli   245 --LSGVMINADAGLAIRGIRH 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31549	NP_730972.2	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	68/278 (24%)
hcaB	NP_417036.1	BphB-like_SDR_c	3..259	CDD:187606	66/273 (24%)