Protein Alignment CG31549 and CBR4

DIOPT Version :10

• Sequence 1: NP_730972.2
• Gene: CG31549 / 40689
• FlyBaseID: FBgn0051549
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: XP_006714454.1
• Gene: CBR4 / 84869
• HGNCID: 25891
• Length: 247
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 91/261 - (34%)
• Similarity: 126/261 - (48%)
• Gaps: 36/261 - (13%)

  Fly     6 DKVIIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKLKETADNIVAAGGATPLELQADMTKEAE 70
            |||..|.|.|.|||.:.|..:|:.|..|.::.||.|..|..|.::    |...|....|:.||.:
Human     2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL----GGDHLAFSCDVAKEHD 62

  Fly    71 VQQIVGATLAKH-GRIDVLVNNAGILETGSIEATSLEQFDRLMNTNVRSLYQLTMLATPELVKTK 134
            ||... ..|.|| ||::.|||.|||...|.:..|..|.....::||:..    :||.....::|.
Human    63 VQNTF-EELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLG----SMLTCKAAMRTM 122

  Fly   135 -----GNIVNVS----------SVCGLRAFPGVLAYNVSKAAVDQFTACIALELAPKGVRVNAVN 184
                 |:||||.          |:.||:...|...|:.||..:..|:..:|.|:|.|.:|||.|.
Human   123 IQQQGGSIVNVGHRREMLLHKRSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 187

  Fly   185 PGVIVTDIHKRGGMDEETYAKFLEHCKITHALGRPGDVKEVAAAIAFLASDQASFTTGISLPVDG 249
            ||.:.||:.|  .:.|       ||.|....|||.|:..|||.|:.||.  ::.:.||..|.|||
Human   188 PGFVHTDMTK--DLKE-------EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDG 241

  Fly   250 G 250
            |
Human   242 G 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31549	NP_730972.2	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	91/261 (35%)
CBR4	XP_006714454.1	Rossmann-fold NAD(P)(+)-binding proteins	3..243	CDD:473865	90/260 (35%)