Protein Alignment CG31549 and DCXR

DIOPT Version :10

• Sequence 1: NP_730972.2
• Gene: CG31549 / 40689
• FlyBaseID: FBgn0051549
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_057370.1
• Gene: DCXR / 51181
• HGNCID: 18985
• Length: 244
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 86/246 - (34%)
• Similarity: 124/246 - (50%)
• Gaps: 19/246 - (7%)

  Fly     9 IIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKLKETADNIV-AAGGATPLELQADMTKEAEVQ 72
            ::||||..|||......|...|..:|.|.|.:..|    |::| ...|..|  :..|:......:
Human    10 VLVTGAGKGIGRGTVQALHATGARVVAVSRTQADL----DSLVRECPGIEP--VCVDLGDWEATE 68

  Fly    73 QIVGATLAKHGRIDVLVNNAGI-LETGSIEATSLEQFDRLMNTNVRSLYQLTMLATPELVK--TK 134
            :.:|:.    |.:|:|||||.: |....:|.|. |.|||....|:|::.|::.:....|:.  ..
Human    69 RALGSV----GPVDLLVNNAAVALLQPFLEVTK-EAFDRSFEVNLRAVIQVSQIVARGLIARGVP 128

  Fly   135 GNIVNVSSVCGLRAFPGVLAYNVSKAAVDQFTACIALELAPKGVRVNAVNPGVIVTDIHKRGGMD 199
            |.||||||.|..||......|..:|.|:|..|..:||||.|..:|||||||.|::|.:.:....|
Human   129 GAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSD 193

  Fly   200 EETYAKFLEHCKITHALGRPGDVKEVAAAIAFLASDQASFTTGISLPVDGG 250
            .......|...    .||:..:|:.|..||.||.||::..|||.:|||:||
Human   194 PHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31549	NP_730972.2	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	86/246 (35%)
DCXR	NP_057370.1	XR_like_SDR_c	1..244	CDD:187609	86/246 (35%)